TGFBI gene transcript is transforming growth factor-ß1-responsive and cell density-dependent in a human corneal epithelial cell line

Abstract

The TGFBI gene transcript in this human corneal epithelial cell line is upregulated by growth factor TGF-beta( 1), but is not affected by growth factor EGF. Furthermore, cell density appears to be an important regulatory mechanism in controlling the level of TGFBI gene expression in corneal epithelial cells.