Simultaneous Blockade of Multiple Immune System Inhibitory Checkpoints Enhances Antitumor Activity Mediated by Interleukin-15 in a Murine Metastatic Colon Carcinoma Model - Concepedia

Concepedia

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Simultaneous Blockade of Multiple Immune System Inhibitory Checkpoints Enhances Antitumor Activity Mediated by Interleukin-15 in a Murine Metastatic Colon Carcinoma Model

DOI Full Paper Access

208

Citations

30

References

2010

Year

Ping Yu, Jason C. Steel, Meili Zhang, John C. Morris, Thomas A. Waldmann

Clinical Cancer Research

Abstract

Combining the immune stimulatory properties of IL-15 with the simultaneous removal of 2 critical immune system inhibitory checkpoints, we showed enhancement of immune responses leading to increased antitumor activity.

References

	Year	Citations

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