EFFECT OF ORTHOTOPIC LIVER TRANSPLANTATION ON THE PROGRESSION OF FAMILIAL AMYLOIDOTIC POLYNEUROPATHY

Abstract

Liver transplantation offers the only cure for the genetic defect causing FAP and appears to result in subjective and objective improvement in neurological dysfunction. Patients with preexisting cardiovascular abnormalities progress despite transplantation; therefore, consideration for combined heart-liver transplantation may be warranted in this subset of patients.