Prediction of Response to Pegylated Interferon plus Ribavirin by<i>IL28B</i>Gene Variation in Patients Coinfected with HIV and Hepatitis C Virus

Abstract

IL28B gene variations independently predict SVR in HIV/HCV-coinfected patients with HCV genotype 1 and non-genotype 1 HCV infection. The association between rs12979860 and plasma low-density lipoprotein cholesterol suggests that the system low-density lipoprotein ligand/receptor might be involved in the effect of this genotype.