Natural course of treated and untreated chronic HCV infection: results of the nationwide <i>Hepnet</i>.<i>Greece</i> cohort study

Abstract

IFNalpha-based treatment does alter the natural course of CHC. A protective effect is mostly present in patients with SVR, but older patients, at higher risk of events, gain the greatest benefit. In established cirrhosis, treatment carries a protective effect even among those without SVR.