Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells - Concepedia

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Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells

DOI Full Paper Access

23

Citations

7

References

2010

Year

Sandrine Reigadas, Marie‐Line Andréola, Linda Wittkop, Ophélie Cosnefroy, Guerric Anies, Patrícia Recordon-Pinson, Rodolphe Thiébaut, Bernard Masquelier, Hervé Fleury

Journal of Antimicrobial Chemotherapy

Abstract

In antiretroviral-experienced patients receiving raltegravir, 2-LTR DNA increased while total HIV-1 DNA decreased over time. The frequent rearrangements found in 2-LTR sequences warrant further investigations to determine the dynamics of evolution of unintegrated HIV-1 DNA.

References

	Year	Citations

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