A 3D <i>in Vitro</i> Model Reveals Differences in the Astrocyte Response Elicited by Potential Stem Cell Therapies for CNS Injury

Abstract

This approach can screen therapeutic cells prior to in vivo testing, allowing cells likely to trigger a substantial astrocyte response to be identified at an early stage. NCSCs and differentiated Schwann cell-like adipose-derived stem cells may be useful in treating CNS damage without increasing astrogliosis.