Publication | Open Access
<scp>api</scp>‐<scp>calc</scp> 1.0: a computer program for calculating the average probability of identity allowing for substructure, inbreeding and the presence of close relatives
69
Citations
9
References
2004
Year
Ecological GeneticsGeneticsPi AveGenomicsAverage ProbabilityPhylogenetic AnalysisGenetic DiversityConservation GeneticsDna ProfilingPhylogeneticsMolecular EcologyHuman PhenotypesQuantitative GeneticsStatistical GeneticsComputer ProgramGenetic VariationPopulation GeneticsLinkage DisequilibriumAbstract Individual IdentificationNatural SciencesEvolutionary BiologyPopulation GenomicsMedicineClose Relatives
Abstract Individual identification via DNA profiling is important in molecular ecology, particularly in the case of noninvasive sampling. A key quantity in determining the number of loci required is the probability of identity (PI ave ), the probability of observing two copies of any profile in the population. Previously this has been calculated assuming no inbreeding or population structure. Here we introduce formulae that account for these factors, whilst also accounting for relatedness structure in the population. These formulae are implemented in api ‐ calc 1.0, which calculates PI ave for either a specified value, or a range of values, for F IS and F ST .
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