Angiotensin II Type 1 and 2 Receptors in Conduit Arteries of Normal Developing Microswine

Abstract

A novel AT2R-positive cell layer confined to postnatal infradiaphragmatic arteries physically links adventitial and medial layers, appears optimally positioned to transduce AT2R-dependent functions of local Ang II, and suggests that adventitial Ang II may elicit regionally distinct vascular responses.