Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent - Concepedia

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Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent

190

Citations

28

References

2009

Year

Sandra Larrède, Carmel M. Quinn, Wendy Jessup, Éric Frisdal, Maryline Olivier, Victar Hsieh, Mi‐Jurng Kim, Miranda Van Eck, Philippe Couvert, Alain Carrié,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Our data indicate that stimulation of cholesterol efflux to HDL by LXR agonists in human foam cells involves an ATP-dependent transport mechanism mediated by ABCA1 that it appears to be independent of ABCG1 expression.

References

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