Tissue Antigens · 1976 · 15 citations · 9 references
Life SciencesImmunologyInternal MedicineAutoimmunityClinical ImmunologyRheumatologyAutoimmune Disease Susceptibility GenesAutoimmune DiseasesGenetic Susceptibility To AutoimmunityImmunoglobulin DisordersSjogren SyndromeSjögren SyndromeHla Allele Frequency DistributionHla Genotype AssociationsHla Risk AllelesRelative Risk Estimation
HL-A phenotype frequencies were studied in 36 patients with Sjögren's syndrome and compared with those of 350 healthy individuals from the same geographical area. Patients suffering from Sjögren's syndrome had a significantly higher frequency of HL-A8 (P corrected less than 0.01). The relative risk of developing Sjögren's syndrome is 3.96 for HL-A8 positive individuals.
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