physica status solidi (a) · 2011 · 25 citations · 25 references
EngineeringBioengineeringBiomedical EngineeringBiosensorsInstrumentationSensorsBiological SensorsBiomedical InstrumentationCell-based BiosensorsImpedance SpectroscopyMicrofluidic BiosensorsMicroscale BiosensorsBioanalytical ApplicationsBioanalytical MethodologyBioanalytical MicrosystemsBiosensor CharacterizationHistamine ReceptorsIntegrated Passive ComponentsSensor Impedance Analysis
Abstract A miniaturised, low cost impedance analyser is developed to ease the use of impedance spectroscopy in biological setups. This could form the first step towards fully standalone, hand‐held biosensor applications. The system is capable of performing quasi‐simultaneous time resolved impedance measurements on eight different channels in a frequency range of 10 Hz–100 kHz. The unit is accurate in a broad impedance range and is able to perform stable measurements over intervals of several days. The system is characterised by passive components, a temperature controlled wet cell based impedance setup and a biomimetic molecularly imprinted polymer (MIP) based histamine sensor. The test results all indicate accurate and stable functioning of the unit, making it suitable for bioanalytical applications.
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