Recent Advances in the Measurement of Enantiomeric Excesses

Abstract

The elaboration of an ever increasing number of chiral catalysts or reagents demands fast and sensitive methods to measure enantiomeric excesses of the products. This review discusses the various ways to solve these problems. Mass spectrometry, chromatographic or chiroptical methodologies, fluorescence, liquid crystals, enzymatic methods, and immunoassays, are some of the technologies which may be used. Kinetic resolution is often a convenient and complementary tool for analysing a mixture of enantiomers.