Polarized release of hepatic micro<scp>RNA</scp>s into bile and serum in response to cellular injury and impaired liver function

Abstract

During impaired excretory function and injury, the liver shows polarized release of extracellular HDmiRs and CDmiRs. This sheds new light on the biology of hepatic miRNA release which is relevant for the interpretation of hepatic miRNAs as biomarkers.