Biochemical quality of the pharmaceutically licensed plasma OctaplasLG^® after implementation of a novel prion protein (PrP^Sc) removal technology and reduction of the solvent/detergent (S/D) process time

Abstract

The studies confirmed that the affinity ligand chromatography under the developed conditions can be introduced into the Octaplas manufacturing process, as a mean to reduce potentially present PrP(Sc), without hampering the proven quality of this product.