Expression of transmembrane protein tyrosine phosphatase gamma (PTPγ) in normal and neoplastic human tissues

Abstract

We have analysed PTPgamma expression in archival paraffin-embedded tissues for the first time, demonstrating particularly high expression in endocrine cells and both down- and up-regulation in neoplasia, the latter possibly reflecting the undifferentiated state of the neoplastic cells, suggesting a complex role for this phosphatase.