Molecular Recognition of C₆₀ with γ‐Cyclodextrin

Abstract

Charge-transfer interactions stabilize the 1:2 complex between C60 and γ-cyclodextrin (schematic representation shown on the right). Since it is known that C60 derivatives inhibit, for instance, the HIV-1 protease, this result is also important for the understanding of the molecular recognition of C60 by the hydrophobic pocket of the active site of enzymes.