Journal of Analytical Toxicology · 1988 · 27 citations · 2 references
MedicinePharmacologySurgeryAnesthesiaForensic Pharmaceutical AnalysisPerioperative PharmacologyOpioid PharmacologyPharmacokinetics In SurgeryPostmortem Drug AnalysisBlood Drug AnalysisBlood Drug TestingBlood Opioid TestingPostmortem Blood AnalysisPostmortem Blood CollectionPostmortem Blood Concentration InterpretationPostmortem Opioid AnalysisSample Pre-treatment
Thirty paired samples of plasma and whole hemolyzed blood were obtained from patients undergoing surgery. Morphine concentrations were measured with the DPC serum morphine kit without prior treatment. In a regression analysis, the equation to the regression line was blood = 1.02 plasma + 1.0 ng/mL, and the correlation coefficient was 0.994. Radioimmunoassay screening of postmortem blood samples can be performed without prior sample treatment.
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