Organic Letters · 2009 · 47 citations · 38 references
The total synthesis of gambierol has been achieved utilizing an oxiranyl anion strategy in an iterative manner. Synthetic highlights of this route include direct carbon-carbon formation on epoxides, sulfonyl-assisted 6-endo cyclization, and expansion reaction of tetrahydropyranyl rings to oxepanes to forge the polycyclic architecture of the target molecule.
38
Yoshihiko Ito, Toshikazu Hirao, Takeo Saegusa · The Journal of Organic Chemistry · 1978 · 849 citations
Derivative (Chemistry), .Beta.-unsaturated Carbonyl Compounds, Engineering +12
A stereoselective synthesis of (Z)-1-iodo-1-alkenes
Gilbert Stork, Kang Zhao · Tetrahedron Letters · 1989 · 363 citations
Total Synthesis of (−)-Gambierol
Haruhiko Fuwa, Noriko Kainuma, Kazuo Tachibana et al. · Journal of the American Chemical Society · 2002 · 174 citations