Effect of Silibinin on the Pharmacokinetics of Pyrazinamide and Pyrazinoic Acid in Rats

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Drug Safety, Compromise Treatment, Pulmonary Tuberculosis +15

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients

Thomas W. Flaig, Daniel L. Gustafson, Lih‐Jen Su et al. · Investigational New Drugs · 2006 · 314 citations

Urology, Oncology, Medicine +6

Silymarin protects against paracetamol‐induced lipid peroxidation and liver damage

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Pharmacokinetic studies on IdB 1016, a silybin-phosphatidylcholine complex, in healthy human subjects

N. Barzaghi, Francesca Crema, G. Gatti et al. · European Journal of Drug Metabolism and Pharmacokinetics · 1990 · 221 citations

Pharmacokinetic Studies, Biochemistry, Medicine +5

Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention

Jifu Zhao, Rajesh Agarwal · Carcinogenesis · 1999 · 174 citations

Food Bioactive Compound, Phase Ii, Biochemistry +14