Publication | Open Access

Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin

X-ray CrystallographyMolecular DockingMedicinal ChemistryBiochemistryRational DesignMedicineNatural SciencesRational Drug DesignPharmacotherapyDrug DevelopmentPharmacologyMolecular ModelingDrug Discovery