Cytomegalovirus in Solid Organ Transplantation

Abstract

Cytomegalovirus (CMV) is a ubiquitous herpes virus that infects the majority of humans (1). The seroprevalence rates of CMV ranges from 30–97% (2,3). Primary infection manifests as an asymptomatic or self-limited febrile illness in immunocompetent individuals, after which CMV establishes life-long latency in various cells (2,3), which serve as reservoirs for reactivation and as carriers of infection to susceptible individuals (4,5).