Concepedia

Surfactant‐Type Brønsted Acid Catalyzed Stereoselective Synthesis of <i>trans</i>‐3‐Alkenyl Indazoles from Triazenylaryl Allylic Alcohols in Water

Weijun Yang, Zhigen Yang, Lijun Xu, Lili Zhang, Xin Xu, Maozhong Miao, Hongjun Ren

Angewandte Chemie International Edition · 2013 · 35 citations · 66 references

DOI

Concepts

Abstract

Testing the waters: An efficient dodecyl benzene sulfonic acid (DBSA) catalyzed approach to the synthesis of the title compounds in water is reported. Furthermore, upon cleavage of the pyrrolidine group from the trans-3-alkenyl-2-pyrrolidine-2H-indazoles with Zn in CH3COOH, trans-3-alkenyl-1H-indazoles are obtained in good to excellent yields.

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