Covalently PEGylated Carbon Nanotubes with Stealth Character In Vivo

Abstract

Stealth nanotubes: The stealth character of covalently PEGylated single-walled nanotubes (SWNTs, indicated by arrows in image) in vivo is studied. The nanotubes exhibit much longer blood-circulation half-life in vivo than the previous record for nanotubes and also a low hepatic uptake, vital to uses in drug-delivery systems. The benefits are reflected in the observed high tumor uptake of PEGylated SWNTs.