Angiotensin (1–7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs

Abstract

In endothelial cells angiotensin (1-7) counteracts the negative effects of angiotensin II on insulin signalling and NO production. The balance between angiotensin II and angiotensin (1-7) could represent a key mechanism in the pathophysiological processes leading to endothelial dysfunction and insulin-resistance.