JAMA · 2012 · 484 citations · 67 references
MedicineGeriatric MedicinePharmacotherapyBehavioral MedicineDementiaGeriatric CareBehavioral SymptomsCognitive ImpairmentDementia CareDementia CaregivingDementia TreatmentFunctional Impairment In DementiaAlzheimer Disease ProgressionBehavioral Management In DementiaDementia-related Behavioral Symptom ManagementDementia-related Sleep DisturbanceNonpharmacologic Symptom ManagementNonpharmacological Interventions For DementiaNonpharmacological Treatment Of DementiaTreatment Of Cognitive Symptoms
Behavioral symptoms such as repetitive speech, wandering, and sleep disturbances are a core clinical feature of Alzheimer disease and related dementias. If untreated, these behaviors can accelerate disease progression, worsen functional decline and quality of life, cause significant caregiver distress, and result in earlier nursing home placement. Systematic screening for behavioral symptoms in dementia is an important prevention strategy that facilitates early treatment of behavioral symptoms by identifying underlying causes and tailoring a treatment plan. First-line nonpharmacologic treatments are recommended because available pharmacologic treatments are only modestly effective, have notable risks, and do not effectively treat some of the behaviors that family members and caregivers find most distressing. Examples of nonpharmacologic treatments include provision of caregiver education and support, training in problem solving, and targeted therapy directed at the underlying causes for specific behaviors (eg, implementing nighttime routines to address sleep disturbances). Based on an actual case, we characterize common behavioral symptoms and describe a strategy for selecting evidence-based nonpharmacologic dementia treatments. Nonpharmacologic management of behavioral symptoms in dementia can significantly improve quality of life and patient-caregiver satisfaction.
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Britt Appelhof, Christian Bakker, Jeannette C.L. van Duinen‐van den IJssel et al. · Dementia and Geriatric Cognitive Disorders · 2017 · 2.8K citations · Full text
Dementia: a public health priority
Daisy Acosta, Ennapadam S. Krishnamoorthy, Marc Wortmann et al. · 2012 · 2K citations
Validation of the NPI-Q, a Brief Clinical Form of the Neuropsychiatric Inventory
Daniel Kaufer, Jeffrey L. Cummings, Patrick Ketchel et al. · Journal of Neuropsychiatry · 2000 · 1.9K citations
Medicine, Psychiatry, Dementia +16