Concepedia

Distinct Changes in Serum Fibroblast Growth Factor 21 Levels in Different Subtypes of Diabetes

Yang Xiao, Aimin Xu, Lawrence Siu‐Chun Law, Cheng Chen, Hui Li, Xia Li, Lin Yang, Shiping Liu, Zhiguang Zhou, Karen S.L. Lam

The Journal of Clinical Endocrinology & Metabolism · 2011 · 101 citations · 20 references

DOI

Abstract

Serum FGF21 level is increased in type 2 diabetes but decreased in type 1 diabetes and LADA. In autoimmune diabetes, the reduction in circulating FGF21 is closely associated with markers of pancreatic β-cell autoimmunity.

References

20

Diagnosis and Classification of Diabetes Mellitus

Diabetes Care · 2010 · 14K citations · Full text

Diagnosis and Classification of Diabetes Mellitus

Diabetes Care · 2007 · 1.1K citations

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Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

Xinmei Zhang, Dennis C.Y. Yeung, Michal Karpíšek et al. · Diabetes · 2008 · 883 citations

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

Ffolliott M. Fisher, Patricia C. Chui, Patrick J. Antonellis et al. · Diabetes · 2010 · 812 citations · Full text

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

Klementina Fon Tacer, Angie L. Bookout, Xunshan Ding et al. · Molecular Endocrinology · 2010 · 674 citations · Full text

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