Concepedia

8-Amino-adenosine is a potential therapeutic agent for multiple myeloma

Nancy Krett, Katharine M. Davies, Mary Ayres, Chunguang Ma, Chadi Nabhan, Varsha Gandhi, Steven T. Rosen

Molecular Cancer Therapeutics · 2004 · 32 citations · 29 references

DOI

Abstract

Based on these results, we conclude that 8-NH2-Ado may hold great potential as a therapeutic agent for the treatment of MM.

References

29

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

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Cancer Statistics, 2003

Ahmedin Jemal, Thomas S. Murray, Alicia Samuels et al. · CA A Cancer Journal for Clinicians · 2003 · 3.3K citations · Full text

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A Prospective, Randomized Trial of Autologous Bone Marrow Transplantation and Chemotherapy in Multiple Myeloma

Michel Attal, Jean‐François Rossi, Philippe Casassus et al. · New England Journal of Medicine · 1996 · 2.6K citations · Full text

A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

M Ichel A Ttal, J Ean, A.A. D uuml nne et al. · 2013 · 2.2K citations

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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3

Thomas Wieder, Aram Prokop, Karin Schmelz et al. · Blood · 2001 · 247 citations