Concepedia

Publication | Closed Access

Dexmedetomidine-Induced Sedation in Volunteers Decreases Regional and Global Cerebral Blood Flow

DOI

171

Citations

23

References

2002

Year

Richard C. Prielipp, Michael H. Wall, Joseph R. Tobin, Leanne Groban, Mark A Cannon, Frederic H. Fahey, H. Donald Gage, David A. Stump, Robert L. James, Judy Bennett,
Anesthesia & Analgesia

Abstract

Dexmedetomidine-induced sedation decreased cerebral blood flow (CBF) by congruent with 33%, which could be due to direct alpha(2)-receptor cerebral smooth muscle vasoconstriction or to compensatory CBF changes caused by dexmedetomidine-induced decreases in the cerebral metabolic rate.

References

YearCitations

Page 1