Proenzyme Forms of Prostate-Specific Antigen in Serum Improve the Detection of Prostate Cancer

Abstract

The percentage of proPSA gave better cancer detection in the 4-10 microg/L range than did percentage of free PSA and complexed PSA. (-2)proPSA significantly discriminated cancer in men whose serum had >25% free PSA, for whom there is currently no good marker for cancer detection.