Long non-coding RNA <i>HNF1A-AS1</i> regulates proliferation and migration in oesophageal adenocarcinoma cells

Abstract

We have discovered abnormal upregulation of a lncRNA, HNF1A-AS1, in human EAC. Our findings suggest that dysregulation of HNF1A-AS1 participates in oesophageal tumorigenesis, and that this participation may be mediated, at least in part, by modulation of chromatin and nucleosome assembly as well as by H19 induction.