Apelin Attenuates Hyperoxic Lung and Heart Injury in Neonatal Rats

Yvonne P. de Visser, Frans J. Walther, El Houari Laghmani, Arnoud van der Laarse, Gerry T. M. Wagenaar

American Journal of Respiratory and Critical Care Medicine · 2010 · 98 citations · 55 references

DOIFull text

Open access

Abstract

Apelin reduces pulmonary inflammation, fibrin deposition, and right ventricular hypertrophy, and partially restores alveolarization in rat pups with neonatal hyperoxic lung injury via a nitric oxide synthase-dependent mechanism.

References

55