High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice - Concepedia

Concepedia

Publication | Open Access

High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice

DOI Full Paper Access

141

Citations

49

References

2010

Year

Peter Kanellakis, Alex Agrotis, Tin Kyaw, Christine Koulis, Ingo Ahrens, Shuji Mori, Hideo Takahashi, Keyue Liu, Karlheinz Peter, Masahiro Nishibori,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

HMGB1 exerts proatherogenic effects augmenting lesion development by stimulating macrophage migration, modulating proinflammatory mediators, and encouraging the accumulation of immune and smooth muscle cells.

References

	Year	Citations

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