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TLDR

The study aimed to examine the clinical and historical features and natural history of aneurysmal coronary disease. This was done by reviewing registry data from the Coronary Artery Surgery Study (CASS). Among 978 patients (4.9 % of the registry), aneurysmal coronary disease showed no significant differences in risk factors, clinical presentation, or 5‑year survival compared with non‑aneurysmal disease, indicating it is a variant of coronary atherosclerosis rather than a distinct entity.

Abstract

To examine the clinical and historical features and the natural history of aneurysmal coronary disease, we reviewed the registry data of the Coronary Artery Surgery Study (CASS). Nine hundred seventy-eight patients, representing 4.9% of the total registry population, were identified as having aneurysmal disease. No significant differences were noted between aneurysmal and nonaneurysmal coronary disease patients when features such as hypertension, diabetes, lipid abnormalities, family history, cigarette consumption, incidence of documented myocardial infarction, presence and severity of angina, and presence of peripheral vascular disease were examined. In addition, no difference in 5-year medical survival was noted between these two groups. These findings suggest that aneurysmal coronary disease does not represent a distinct clinical entity but is, rather, a variant of coronary atherosclerosis.

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