N‐Heterocyclic Carbene Catalyzed Reactions of α‐Bromo‐α,β‐unsaturated Aldehydes/α,β‐Dibromoaldehydes with 1,3‐Dinucleophilic Reagents

Abstract

Carbenes ring true: N-Heterocyclic carbene (NHC) catalyzed reactions of α-bromo-α,β-unsaturated aldehydes/α,β-dibromoaldehydes with 1,3-dinucleophilic reagents, such as 1,3-dicarbonyl compounds, β-enamino ketones, and β-enamino esters through umpolung processes gave functionalized 3,4-dihydropyranones and 3,4-dihydropyridinones. The availability of the starting materials, lack of external oxidant, and usefulness of the products make this strategy attractive.