Polymorphism of angiotensin I converting enzyme gene in the older Chinese: linked to ambulatory blood pressure levels and circadian blood pressure rhythm

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

Hypertension, Healthy Subjects, Ace Genotype +20

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

Brigitte Rigat, Christine Hübert, Pierre Corvol et al. · Nucleic Acids Research · 1992 · 1.3K citations · Full text

Engineering, Genetics, Enzyme Gene +7

Circadian blood pressure changes and left ventricular hypertrophy in essential hypertension.

Paolo Verdecchia, Giuseppe Schillaci, M Guerrieri et al. · Circulation · 1990 · 1.2K citations

Hypertension, Heart Failure, Blood Pressure Variability +21

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

G I Bell, J H Karam, W J Rutter · Proceedings of the National Academy of Sciences · 1981 · 900 citations

Chromatin, Genetic Analysis, Genetic Determinant +15

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

Howard J. Jacob, Klaus Lindpaintner, Stephen E. Lincoln et al. · Cell · 1991 · 720 citations

Hypertension, Genetic Determinant, Developmental Biology +10