High-Yielding Oxidation of β-Hydroxyketones to β-Diketones Using <i>o</i>-Iodoxybenzoic Acid

Abstract

The oxidation of β-hydroxyketones to β-diketones was systematically investigated. o-Iodoxybenzoic acid (IBX) was found to be efficient, operationally easy, and superior to other common oxidants. The reaction is suitable for milligram- to gram-scale oxidations.