Concepedia

Publication | Open Access

Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

DOIFull Paper Access

351

Citations

24

References

2010

Year

Yasuo To, Kazuhiro Ito, Yasuo Kizawa, Marco Failla, Misako Ito, Tadashi Kusama, W. Mark Elliott, James C. Hogg, Ian M. Adcock, Peter J. Barnes
American Journal of Respiratory and Critical Care Medicine

Abstract

Inhibition of oxidative stress dependent PI3K-δ activation by a selective inhibitor or theophylline provides a novel approach to reversing corticosteroid insensitivity in COPD.

References

YearCitations

Page 1