Molecular Cell · 2015 · 162 citations · 29 references
Life SciencesBiochemistryMolecular BiologyMolecular PharmacologyStructural BiologyStructure-activity RelationshipsEnzyme InhibitionLigand BindingMolecular DockingProtein StructureProtein-ligand DockingStructure-activity Relationship AnalysisEif4f Complex RegulationEukaryotic Initiation Factor 4EEukaryotic Initiation Factor 4F ComplexMolecular Architecture ControlMolecular Docking Of Inhibitors
29
The translational landscape of mTOR signalling steers cancer initiation and metastasis
Andrew C. Hsieh, Yi Liu, Merritt P. Edlind et al. · Nature · 2012 · 1.4K citations
Medicine, Cancer Biology, Oncology +14
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
Anne‐Claude Gingras, Steven P. Gygi, Brian Raught et al. · Genes & Development · 1999 · 1.3K citations · Full text
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
Anne‐Claude Gingras, Brian Raught, Steven P. Gygi et al. · Genes & Development · 2001 · 884 citations · Full text
mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
Ryan J.O. Dowling, Ivan Topisirović, Tommy Alain et al. · Science · 2010 · 755 citations
Sylvie Mader, Han Lee, Arnim Pause et al. · Molecular and Cellular Biology · 1995 · 673 citations · Full text