<scp>HNA</scp>‐1d: a new human neutrophil antigen located on <scp>Fc</scp>γ receptor <scp>IIIb</scp> associated with neonatal immune neutropenia

Abstract

A previously unrecognized second antigen, HNA-1d, is present on FcγRIIIb encoded by FCGR3B*02. This antigen is characterized by the sequence Ala78---Asn82. It appears that only individuals carrying the HNA-1c phenotype can form anti-HNA-1d alloantibodies. The HNA-1 system now consists of four antigens encoded by three alleles.