Influence of Both a Static Magnetic Field and Penetratin on Magnetic Nanoparticle Delivery into Fibroblasts

Abstract

Modeling of the field applied demonstrated varying field patterns across the cell culture area, reflected by higher particle uptake at higher field strengths. Both penetratin and the magnetic field increased cell uptake with penetratin proving more efficient. Interestingly, the magnetic field stimulated clathrin-mediated endocytosis and subsequent particle uptake.