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Knockout of the Mouse Glutamate Cysteine Ligase Catalytic Subunit (Gclc) Gene: Embryonic Lethal When Homozygous, and Proposed Model for Moderate Glutathione Deficiency When Heterozygous

Cellular EnzymologyBiochemistryGenetic DisorderNatural SciencesGeneticsBiochemical GeneticsMolecular BiologyEmbryonic LethalMedicineModerate Glutathione DeficiencyOxidative Stress