High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock

APACHE II

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations

Medicine, Internal Medicine, Clinical Classification Systems +16

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William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1986 · 13.4K citations

Health Professions, Biostatistics, Clinical Classification Systems +12

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

Jean‐Louis Vincent, Rui P. Moreno, Jukka Takala et al. · Intensive Care Medicine · 1996 · 11.6K citations

Veterinary Medicine, Internal Medicine, Critical Care Medicine +12

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.8K citations · Full text

Veterinary Medicine, Immunology, Pharmacotherapy +15

Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey Lidicker et al. · Critical Care Medicine · 2001 · 8.6K citations

Veterinary Medicine, Infectious Diseases, Internal Medicine +16