Extracellular DNA oxidation stimulates activation of NRF2 and reduces the production of ROS in human mesenchymal stem cells - Concepedia

Concepedia

Publication | Closed Access

Extracellular DNA oxidation stimulates activation of NRF2 and reduces the production of ROS in human mesenchymal stem cells

49

Citations

23

References

2012

Year

Polina Loseva, Svetlana V. Kostyuk, Elena M. Malinovskaya, N Clément, CA Dechesne, Christian Dani, K. V. Glebova, Ancha Baranova, E. K. Ginter

Expert Opinion on Biological Therapy

Abstract

Oxidized cfDNA up-regulates NRF2 and PPARG2 and reduces ROS production in MSCs. These effects should be taken into account when considering therapeutic applications of stem cells.

References

	Year	Citations

Page 1