Angewandte Chemie International Edition · 2002 · 99 citations · 0 references
Life SciencesImmunologyOncologyCancer ImmunologyCarbohydrate ChemistryAntigen DesignCarbohydrate ReactivityCarbohydrate RecognitionCarbohydrate SynthesisTumor-associated AntigensCarbohydrate Antigen DesignCarbohydrate Building Block SynthesisCarbohydrate Tumor AntigensOne-pot Oligosaccharide SynthesisStereospecific ReactionsTumor-associated Carbohydrate Antigens
The stereospecific synthesis of a tumor-related carbohydrate antigenic hapten, Lewis Y, from three basic building units 1–3 has been achieved by a reactivity-based one-pot strategy. RRV=relative reactivity value.