Electrochemical Aerobic Oxidation of Aminocyclopropanes to Endoperoxides

Abstract

Electrical synthesizer: Results of cyclic voltammetric studies on a range of aminocyclopropanes in the absence or in the presence of oxygen are in full agreement with the currently accepted autocatalytic mechanism for the aerobic oxidation of these compounds. A simple and efficient procedure was developed for the electrosynthesis of the corresponding endoperoxides (see scheme), some of which exhibit moderate antimalarial activity. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z702903_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.