Journal of Histochemistry & Cytochemistry · 1960 · 267 citations · 2 references
Life SciencesBiochemistryMolecular BiologyEnzymologyGlycobiologyHistopathologyHistological StainingImmunohistochemistryHistochemical MarkersHistochemical MicroscopyMucin BiologyMucin Glycan AnalysisMucopolysaccharide AnalysisSialic Acid LabelingSialic Acid ReleaseSialylation Analysis
Sialidase digestion of histological sections releases sialic acid from some sialic acid rich nonsulfated mucins. Such treatment eliminates the metachromatic staining and alcian blue affinity of these mucopolysaccharides. The procedure furnishes a method for histochemical localization of certain sialomucins.
2