Transepidermal water loss, serum IgE and<i>β</i>-endorphin as important and independent biological markers for development of itch intensity in atopic dermatitis

Abstract

Beta-endorphin and IgE are both useful biomarkers for itch and disease severity in patients with AD, while TEWL is a good biomarker for itch intensity. These biomarkers provide a way to assess the itch intensity in patients with AD.