Association of the CTLA4 promoter region (−1661G allele) with type 1 diabetes in the South Moroccan population

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

Life Sciences, Genetics, Molecular Biology +14

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

Elizabeth Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity · 1995 · 2.9K citations · Full text

Life Sciences, Immunology, Pathology +14

Haplotype tagging for the identification of common disease genes

Gillian C.L. Johnson, Laura Esposito, Bryan J. Barratt et al. · Nature Genetics · 2001 · 1.2K citations

Life Sciences, Bioinformatics, Genetics +14

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

Lorenza Nisticò · Human Molecular Genetics · 1996 · 803 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location

Katherine L. Harper, Christine Balzano, Éric Rouvier et al. · The Journal of Immunology · 1991 · 428 citations

Life Sciences, Immunology, Molecular Biology +16