Multiparametric MRI assessment of human articular cartilage degeneration: Correlation with quantitative histology and mechanical properties

Abstract

MRI parameters were able to differentiate between early and advanced OA. Furthermore, rotating frame methods, namely adiabatic T_1ρ , adiabatic T_2ρ , CW-T_1ρ , and RAFF, as well as MT experiment correlated strongly with biomechanical parameters and OARSI grade, suggesting high sensitivity of the parameters for cartilage degeneration. Magn Reson Med 74:249-259, 2015. © 2014 Wiley Periodicals, Inc.